The exocrine secretory part consists of serous acini (known as pancreatic acini), whereas the islets of Langerhans form the endocrine part The major part of pancreas corresponds to the exocrine part (99 % in humans) The serous exocrine cells show a rounded nucleus and dark cytoplasmPancreatic Histology Exocrine Tissue The pancreas is surrounded by a very thin connective tissue capsule that invaginates into the gland to form septae, which serve as scaffolding for large blood vessels Further, these septae divide the pancreas into distinctive lobules, as can clearly be seen in the image of mouse pancreas below (H&E)An essential pancreatic function is the conversion of food into fuel for the body's cells The exocrine part produces mainly digestive enzymes and helps in digestion, whereas the endocrine part is responsible for the regulation of carbohydrate metabolism (ie blood
Endocrine Pancreas
Exocrine vs endocrine pancreas histology
Exocrine vs endocrine pancreas histology-Pancreatic Histology Endocrine Tissue If you examine a section of pancreas at low magnification, you will undoubtedly observe distinctive areas of pale staining embedded within the exocrine tissue of lobules (marked with a red * below) These are the Islets of Langerhans, the endocrine component of the pancreasThe endocrine pancreatic tissue consists of small, discrete clusters of cells, called islets of Langerhans (also called pancreatic islets), scattered throughout the exocrine pancreatic lobules Unlike the exocrine pancreatic acini, which secrete into a ductular system, cells of the islets of Langerhans secrete directly into small fenestrated capillaries that are integrated within
Up to10%cash backThe exocrine secretion products are collected and delivered by a duct system which is drained by the pancreatic ducts The endocrine component is composed of small clumps of cells, named the islets of Langerhans, which are scattered throughout the exocrine glandular tissue The history of the endocrine pancreas has been recently reviewed (S amols230 Pancreas Endocrine Pancreas View Virtual EM Slide You will not be ask to identify different types of endocrine cells in the islet of Langerhans However, compare the appearance of an endocrine cell containing small granules to that of a portion of exocrine cell shown on the rightThe endocrine component of the pancreas consists of the islets of Langerhans, the round masses of glandular epithelial cells appearing as nodules in the endocrine pancreas The cells are found in irregular cords and clumps, as opposed to the neighboring, highly organized acini of the exocrine pancreas They are surrounded by a network of capillaries
The morphology of the exocrine secretory unit of the pancreas, ie the pancreatic acinus, is reviewed The histological features of the acini and their relation with the duct system are described The acinar three‐dimensional architecture was studied by means of different ultrastructural techniques, some of which are complementaryExocrineArranged as pancreatic acinar cellsProduct released into ductal systemSecretions=zymogens and bicarbonate EndocrineArranged as islets of LangerhansProduct released into bloodSecretions=hormonesExocrinereleases enzymes aiding in digestion Endocrine pancreascomponents produced by islets>bloodstream
The pancreas is both an exocrine accessory digestive organ and a hormone secreting endocrine gland The bulk of the pancreatic tissue is formed by the exocrine component, which consists of many serous pancreatic acini cells These acini synthesize and secrete a variety of enzymes essential to successfully "rest and digest"Exocrine part of the pancreas Histologically, the exocrine part of the pancreas shows the typical structure of the serous gland and represents roughly 98% of the organ's tissue The acini consist of strong basophilic cells, which contain numerous secretory granules Acini are made of zymogenic cells that surround a central lumen and are arranged in lobulesThe pancreas is both an exocrine and an endocrine gland The endocrine pancreas consists of accumulations of palestaining cells called islets of Langerhans, which are surrounded by pancreatic acini The islet is composed of different populations of cells that secrete insulin, glucagon, somatostatin or pancreatic polypeptide
Some glands retain their continuity with the surface via a duct and are known as EXOCRINE GLANDS Other glands lose this direct continuity with the surface when their ducts degenerate during development These glands are known as ENDOCRINE glands show labels This is the parotid gland, a type of salivary glandUp to10%cash backThe exocrine secretion products are collected and delivered by a duct system which is drained by the pancreatic ducts The endocrine component is composed of small clumps of cells, named the islets of Langerhans, which are scattered throughout the exocrine glandular tissue The history of the endocrine pancreas has been recently reviewed (SamolsA brief review of the normal histology of the pancreas, as presented by the URMC Pathology IT Program
Exocrine vs Endocrine Fundamentally, the difference between exocrine and endocrine is exocrine secretes (via ducts) to an external surface or body cavity endocrine secretes within an enclosed system eg the bloodstream As the acini of the pancreas secrete into a network of ducts, this gives this organ an exocrine function
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